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Enzyme Tied to Aging in Immune System Found
2025-04-29 11:45:04| Spiritual Career Counseling
University of California - San Diego Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, however, thanks to a new study in GeroScience."Immune cell changes occur during aging for a number of reasons, but we still don't completely understand why we have fewer antibody-producing cells with age," said Leslie Crews, Ph.D., assistant professor of medicine at University of California San Diego School of Medicine, co-leader of the Hematologic Malignancies Research Program at UC San Diego Moores Cancer Center, and a member of the university's Sanford Stem Cell Institute.Crews' lab, in collaboration with researchers at UC Irvine, has found that decreased function of an enzyme called ELOVL2 (short for "elongation of very long chain fatty acids-like 2") speeds up immune system changes associated with aging. ELOVL2 plays a critical role in synthesizing...
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